Via the TIMELINE feature, the user will be able to configure a number of different tests, according to the specific experimental needs, namely the classical shuttle-box tests in its various modes.
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The Active Avoidance set-up is part of UB conditioning-cage project; you buy a single touch-screen controller, and manage all UB cages. Ask for details!
Active avoidance is a fear-motivated associative avoidance task. In this task the animal has to learn to predict the occurrence of an aversive event (shock) based on the presentation of a specific stimulus (tone), in order to avoid the aversive event by moving to a different compartment.
The measures recorded include number of avoidances (the mouse crossing to the other compartment during the warning signal), number of non-responses (the mouse failing to cross to the other compartment during the trial), response latency (latency to avoid or escape), number of intertrial responses (i.e., crossing the barrier within the intertrial interval), and serve as an index of learning and allows memory to be assessed.
Ugo Basile Active Avoidance set-up instrument basically consists of a Controller, and a Cage for either rat or mouse. The tests are conducted in a cage, divided into two sections by a partition with an intercommunicating opening at floor level.
The tilting floor ensures a simple and relaible detection mechanism to score the animal’s movement across the two compartments. The electronic unit encompasses all controls for up to 4 cages and a scrambling shocker.
